Ingredient

N-Hydroxysuccinimide and Chrysin

A paired ingredient combination that supports the clearance of blood pigments beneath the eye - addressing a biological cause of persistent dark circles rather than masking them.

  • Best for

    Persistent Dark Circles

  • Best to

    Clear + Brighten + Reveal

  • Target

    Heme Pigment Accumulation

  • Use

    AM + PM

N-Hydroxysuccinimide and Chrysin

What is it

What are N-Hydroxysuccinimide and Chrysin?

N-Hydroxysuccinimide and chrysin are specifically paired to address one of the most challenging causes of dark circles: the accumulation of iron-rich blood pigments under the eye. As small capillaries near the surface of the under-eye skin break down over time, they release pigments that become trapped and visible - creating the persistent dark coloration that can be present even when well-rested. This combination supports the clearance and breakdown of these heme pigments at the biochemical root.

MDAiRE ingredient benefits — ecm-eye

Benefits

What do N-Hydroxysuccinimide and Chrysin do for your skin?

This ingredient pair targets the underlying cause of dark circles - pigmented blood byproducts - rather than simply masking the appearance of discoloration. Key actions include:

  • Targets the underlying cause of dark circles - pigmented blood byproducts
  • Supports the clearance of heme-related discoloration
  • Improves the appearance of dark under-eye coloration over time
  • Works synergistically with caffeine and niacinamide for compounded results
  • Specifically formulated for the delicate eye area
MDAiRE ingredient how to_use — ecm-eye

How to use

How do N-Hydroxysuccinimide and Chrysin fit your routine?

Found in targeted eye treatments for daily morning and evening use. Apply using the ring finger to pat gently around the orbital bone. Visible results typically develop over 8-12 weeks of consistent use.

Who should use it

Who should use N-Hydroxysuccinimide and Chrysin?

Particularly valuable for those with persistent dark circles that do not respond to surface-level treatments. Especially useful when circles are pigment-related rather than shadow-based. Appropriate for all skin types.

Formulated with

MDAiRE products formulated with N-Hydroxysuccinimide and Chrysin

Regenerative ECM Eye Complex on white background

Regenerative ECM Eye Complex

Reduce dark circles, puffiness, and fine lines using clinical actives formulated specifically for the delicate eye area where...

$122.00
(118)

Not sure if this is right for you?

Let Dr. Kappel build your routine

Take the 1-minute skincare quiz and get a personalized product recommendation.